The UPR consists of signaling pathways that elicit responses that could either keep the cell alive or induce apoptosis. Its direct influence on cell survival has been linked to medical conditions, such as diabetes, Alzheimer’s, and cancer. Led by Dr. Maurizio Zanetti, researchers at the UCSD Laboratory of Immunology have devoted their efforts to studying the UPR’s association with cancer cells and their exploitation of the response to promote tumor growth and protection. Read More